Women’s Health Bulletin

Published by: Kowsar

A Narrative Review of Obesity and Its Associated Complications in Iranian Women

Parvin Mirmiran 1 , 2 , * , Zeinab Ghorbani 1 and Firoozeh Hosseini-Esfahani 1
Authors Information
1 Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Article information
  • Women's Health Bulletin: April 2017, 4 (2); e40546
  • Published Online: January 31, 2017
  • Article Type: Review Article
  • Received: July 5, 2016
  • Revised: January 14, 2017
  • Accepted: January 21, 2017
  • DOI: 10.17795/whb-40546

To Cite: Mirmiran P, Ghorbani Z, Hosseini-Esfahani F. A Narrative Review of Obesity and Its Associated Complications in Iranian Women, Women Health Bull. 2017 ; 4(2):e40546. doi: 10.17795/whb-40546.

Copyright © 2017, Health Policy Research Center, Shiraz University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Context
2. Evidence Acquisition
3. Results
4. Conclusions
  • 1. Jafari-Adli S, Jouyandeh Z, Qorbani M, Soroush A, Larijani B, Hasani-Ranjbar S. Prevalence of obesity and overweight in adults and children in Iran; a systematic review. J Diabetes Metab Disord. 2014; 13(1): 121[DOI][PubMed]
  • 2. Ryan DH, Braverman-Panza J. Obesity in women. J Fam Pract. 2014; 63(2 Suppl): 15-20[PubMed]
  • 3. Garber AJ. Obesity and type 2 diabetes: which patients are at risk? Diabetes Obes Metab. 2012; 14(5): 399-408[DOI][PubMed]
  • 4. Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014; 384(9945): 766-81[DOI][PubMed]
  • 5. Barzin M, Keihani S, Hosseinpanah F, Serahati S, Ghareh S, Azizi F. Rising trends of obesity and abdominal obesity in 10 years of follow-up among Tehranian adults: Tehran Lipid and Glucose Study (TLGS). Public Health Nutr. 2015; 18(16): 2981-9[DOI][PubMed]
  • 6. Faam B, Hosseinpanah F, Amouzegar A, Ghanbarian A, Asghari G, Azizi F. Leisure-time physical activity and its association with metabolic risk factors in Iranian adults: Tehran Lipid and Glucose Study, 2005-2008. Prev Chronic Dis. 2013; 10: 36[DOI][PubMed]
  • 7. Hosseinpanah F, Mirbolouk M, Mossadeghkhah A, Barzin M, Serahati S, Delshad H, et al. Incidence and potential risk factors of obesity among Tehranian adults. Prev Med. 2016; 82: 99-104[DOI][PubMed]
  • 8. Ryan D. Obesity in women: a life cycle of medical risk. Int J Obes (Lond). 2007; 31 Suppl 2: 3-7[DOI][PubMed]
  • 9. Kuczmarski RJ, Flegal KM. Criteria for definition of overweight in transition: background and recommendations for the United States. Am J Clin Nutr. 2000; 72(5): 1074-81[PubMed]
  • 10. Hurley KM, Oberlander SE, Merry BC, Wrobleski MM, Klassen AC, Black MM. The healthy eating index and youth healthy eating index are unique, nonredundant measures of diet quality among low-income, African American adolescents. J Nutr. 2009; 139(2): 359-64[DOI][PubMed]
  • 11. Azizi F, Khalili D, Aghajani H, Esteghamati A, Hosseinpanah F, Delavari A, et al. Appropriate waist circumference cut-off points among Iranian adults: the first report of the Iranian National Committee of Obesity. Arch Iran Med. 2010; 13(3): 243-4[PubMed]
  • 12. Martin KS, Ferris AM. Food insecurity and gender are risk factors for obesity. J Nutr Educ Behav. 2007; 39(1): 31-6[DOI][PubMed]
  • 13. Micklesfield LK, Lambert EV, Hume DJ, Chantler S, Pienaar PR, Dickie K, et al. Socio-cultural, environmental and behavioural determinants of obesity in black South African women. Cardiovasc J Afr. 2013; 24(9-10): 369-75[DOI][PubMed]
  • 14. Barnes AS. Emerging modifiable risk factors for cardiovascular disease in women: obesity, physical activity, and sedentary behavior. Tex Heart Inst J. 2013; 40(3): 293-5[PubMed]
  • 15. Coll JL, Bibiloni Mdel M, Salas R, Pons A, Tur JA. Prevalence and Related Risk Factors of Overweight and Obesity among the Adult Population in the Balearic Islands, a Mediterranean Region. Obes Facts. 2015; 8(3): 220-33[DOI][PubMed]
  • 16. Gangwisch JE, Malaspina D, Boden-Albala B, Heymsfield SB. Inadequate sleep as a risk factor for obesity: analyses of the NHANES I. Sleep. 2005; 28(10): 1289-96[PubMed]
  • 17. Hasler G, Buysse DJ, Klaghofer R, Gamma A, Ajdacic V, Eich D, et al. The association between short sleep duration and obesity in young adults: a 13-year prospective study. Sleep. 2004; 27(4): 661-6[PubMed]
  • 18. Reilly JJ, Armstrong J, Dorosty AR, Emmett PM, Ness A, Rogers I, et al. Early life risk factors for obesity in childhood: cohort study. BMJ. 2005; 330(7504): 1357[DOI][PubMed]
  • 19. Sun J, Buys NJ, Hills AP. Dietary pattern and its association with the prevalence of obesity, hypertension and other cardiovascular risk factors among Chinese older adults. Int J Environ Res Public Health. 2014; 11(4): 3956-71[DOI][PubMed]
  • 20. Hu FB, Li TY, Colditz GA, Willett WC, Manson JE. Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA. 2003; 289(14): 1785-91[DOI][PubMed]
  • 21. Doo M, Kim Y. Obesity: interactions of genome and nutrients intake. Prev Nutr Food Sci. 2015; 20(1): 1-7[DOI][PubMed]
  • 22. Grineva EN, Karonova T, Micheeva E, Belyaeva O, Nikitina IL. Vitamin D deficiency is a risk factor for obesity and diabetes type 2 in women at late reproductive age. Aging (Albany NY). 2013; 5(7): 575-81[DOI][PubMed]
  • 23. Tamer G, Mesci B, Tamer I, Kilic D, Arik S. Is vitamin D deficiency an independent risk factor for obesity and abdominal obesity in women? Endokrynol Pol. 2012; 63(3): 196-201[PubMed]
  • 24. Ning F, Pang Z, Laatikainen T, Gao W, Wang S, Zhang L, et al. Joint effect of family history of diabetes with obesity on prevalence of type 2 diabetes mellitus among Chinese and Finnish men and women. Can J Diabetes. 2013; 37(2): 65-71[DOI][PubMed]
  • 25. Staimez LR, Weber MB, Narayan KM, Oza-Frank R. A systematic review of overweight, obesity, and type 2 diabetes among Asian American subgroups. Curr Diabetes Rev. 2013; 9(4): 312-31[PubMed]
  • 26. Gill RS, Sharma AM, Gill SS, Birch DW, Karmali S. The impact of obesity on diabetes mellitus and the role of bariatric surgery. Maturitas. 2011; 69(2): 137-40[DOI][PubMed]
  • 27. Shang X, Li J, Tao Q, Li J, Li X, Zhang L, et al. educational level, obesity and incidence of diabetes among Chinese adult men and women aged 18-59 years old: an 11-year follow-up study. PLoS One. 2013; 8(6)[DOI][PubMed]
  • 28. Hu Y, Bhupathiraju SN, de Koning L, Hu FB. Duration of obesity and overweight and risk of type 2 diabetes among US women. Obesity (Silver Spring). 2014; 22(10): 2267-73[DOI][PubMed]
  • 29. Derakhshan A, Sardarinia M, Khalili D, Momenan AA, Azizi F, Hadaegh F. Sex specific incidence rates of type 2 diabetes and its risk factors over 9 years of follow-up: Tehran Lipid and Glucose Study. PLoS One. 2014; 9(7)[DOI][PubMed]
  • 30. Hadaegh F, Zabetian A, Harati H, Azizi F. The prospective association of general and central obesity variables with incident type 2 diabetes in adults, Tehran lipid and glucose study. Diabetes Res Clin Pract. 2007; 76(3): 449-54[DOI][PubMed]
  • 31. Hosseinpanah F, Barzin M, Sheikholeslami F, Azizi F. Effect of different obesity phenotypes on cardiovascular events in Tehran Lipid and Glucose Study (TLGS). Am J Cardiol. 2011; 107(3): 412-6[DOI][PubMed]
  • 32. Hadaegh F, Zabetian A, Sarbakhsh P, Khalili D, James WP, Azizi F. Appropriate cutoff values of anthropometric variables to predict cardiovascular outcomes: 7.6 years follow-up in an Iranian population. Int J Obes (Lond). 2009; 33(12): 1437-45[DOI][PubMed]
  • 33. Mohebi R, Bozorgmanesh M, Azizi F, Hadaegh F. Effects of obesity on the impact of short-term changes in anthropometric measurements on coronary heart disease in women. Mayo Clin Proc. 2013; 88(5): 487-94[DOI][PubMed]
  • 34. Petrenya N, Brustad M, Dobrodeeva L, Bichkaeva F, Lutfalieva G, Cooper M, et al. Obesity and obesity-associated cardiometabolic risk factors in indigenous Nenets women from the rural Nenets Autonomous Area and Russian women from Arkhangelsk city. Int J Circumpolar Health. 2014; 73: 23859[DOI][PubMed]
  • 35. Rheaume C, Arsenault BJ, Despres JP, Boekholdt SM, Wareham NJ, et al. Impact of abdominal obesity and systemic hypertension on risk of coronary heart disease in men and women: the EPIC-Norfolk Population Study. J Hypertens. 2014; 32(11): 2224-30[DOI][PubMed]
  • 36. Gill SK. Cardiovascular risk factors and disease in women. Med Clin North Am. 2015; 99(3): 535-52[DOI][PubMed]
  • 37. Meyer MR, Clegg DJ, Prossnitz ER, Barton M. Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors. Acta Physiol (Oxf). 2011; 203(1): 259-69[DOI][PubMed]
  • 38. Keihani S, Hosseinpanah F, Barzin M, Serahati S, Doustmohamadian S, Azizi F. Abdominal obesity phenotypes and risk of cardiovascular disease in a decade of follow-up: the Tehran Lipid and Glucose Study. Atherosclerosis. 2015; 238(2): 256-63[DOI][PubMed]
  • 39. Bastien M, Poirier P, Lemieux I, Despres JP. Overview of epidemiology and contribution of obesity to cardiovascular disease. Prog Cardiovasc Dis. 2014; 56(4): 369-81[DOI][PubMed]
  • 40. Dag ZO, Dilbaz B. Impact of obesity on infertility in women. J Turk Ger Gynecol Assoc. 2015; 16(2): 111-7[DOI][PubMed]
  • 41. Leddy MA, Power ML, Schulkin J. The impact of maternal obesity on maternal and fetal health. Rev Obstet Gynecol. 2008; 1(4): 170-8[PubMed]
  • 42. Kumbak B, Oral E, Bukulmez O. Female obesity and assisted reproductive technologies. Semin Reprod Med. 2012; 30(6): 507-16[DOI][PubMed]
  • 43. Turcksin R, Bel S, Galjaard S, Devlieger R. Maternal obesity and breastfeeding intention, initiation, intensity and duration: a systematic review. Matern Child Nutr. 2014; 10(2): 166-83[DOI][PubMed]
  • 44. Tenenbaum-Gavish K, Hod M. Impact of maternal obesity on fetal health. Fetal Diagn Ther. 2013; 34(1): 1-7[DOI][PubMed]
  • 45. DeJoy SB, Bittner K. Obesity stigma as a determinant of poor birth outcomes in women with high BMI: a conceptual framework. Matern Child Health J. 2015; 19(4): 693-9[DOI][PubMed]
  • 46. Xie Y, Xiong X, Elkind-Hirsch KE, Pridjian G, Maney P, Delarosa RL, et al. Prepregnancy obesity and periodontitis among pregnant females with and without gestational diabetes mellitus. J Periodontol. 2014; 85(7): 890-8[DOI][PubMed]
  • 47. Galliano D, Bellver J. Female obesity: short- and long-term consequences on the offspring. Gynecol Endocrinol. 2013; 29(7): 626-31[DOI][PubMed]
  • 48. Drake AJ, Reynolds RM. Impact of maternal obesity on offspring obesity and cardiometabolic disease risk. Reproduction. 2010; 140(3): 387-98[DOI][PubMed]
  • 49. Thrift AP, Callaway LK. The effect of obesity on pregnancy outcomes among Australian Indigenous and non-Indigenous women. Med J Aust. 2014; 201(10): 592-5[PubMed]
  • 50. Heidari Z, Hosseinpanah F, Barzin M, Safarkhani M, Azizi F. Mother-daughter correlation of central obesity and other noncommunicable disease risk factors: Tehran Lipid and Glucose Study. Asia Pac J Public Health. 2015; 27(2)-9[DOI][PubMed]
  • 51. Simmons D. Diabetes and obesity in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2011; 25(1): 25-36[DOI][PubMed]
  • 52. Ma RC, Chan JC, Tam WH, Hanson MA, Gluckman PD. Gestational diabetes, maternal obesity, and the NCD burden. Clin Obstet Gynecol. 2013; 56(3): 633-41[DOI][PubMed]
  • 53. Herring SJ, Oken E. Obesity and diabetes in mothers and their children: can we stop the intergenerational cycle? Curr Diab Rep. 2011; 11(1): 20-7[DOI][PubMed]
  • 54. Roman AS, Rebarber A, Fox NS, Klauser CK, Istwan N, Rhea D, et al. The effect of maternal obesity on pregnancy outcomes in women with gestational diabetes. J Matern Fetal Neonatal Med. 2011; 24(5): 723-7[DOI][PubMed]
  • 55. Marchi J, Berg M, Dencker A, Olander EK, Begley C. Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews. Obes Rev. 2015; 16(8): 621-38[DOI][PubMed]
  • 56. Pedersen SD. Metabolic complications of obesity. Best Pract Res Clin Endocrinol Metab. 2013; 27(2): 179-93[DOI][PubMed]
  • 57. Barber TM, Vojtechova P, Franks S. The impact of hyperandrogenism in female obesity and cardiometabolic diseases associated with polycystic ovary syndrome. Horm Mol Biol Clin Investig. 2013; 15(3): 91-103[DOI][PubMed]
  • 58. Robker RL, Wu LL, Yang X. Inflammatory pathways linking obesity and ovarian dysfunction. J Reprod Immunol. 2011; 88(2): 142-8[DOI][PubMed]
  • 59. Al-Nuaim LA. The impact of obesity on reproduction in women. Saudi Med J. 2011; 32(10): 993-1002[PubMed]
  • 60. Boeing H. Obesity and cancer--the update 2013. Best Pract Res Clin Endocrinol Metab. 2013; 27(2): 219-27[DOI][PubMed]
  • 61. Louie SM, Roberts LS, Nomura DK. Mechanisms linking obesity and cancer. Biochim Biophys Acta. 2013; 1831(10): 1499-508[DOI][PubMed]
  • 62. Simpson ER, Brown KA. Obesity and breast cancer: role of inflammation and aromatase. J Mol Endocrinol. 2013; 51(3)-9[DOI][PubMed]
  • 63. Vona-Davis L, Rose DP. Type 2 diabetes and obesity metabolic interactions: common factors for breast cancer risk and novel approaches to prevention and therapy. Curr Diabetes Rev. 2012; 8(2): 116-30[PubMed]
  • 64. Bozkurt L, Gobl CS, Pfligl L, Leitner K, Bancher-Todesca D, Luger A, et al. Pathophysiological characteristics and effects of obesity in women with early and late manifestation of gestational diabetes diagnosed by the International Association of Diabetes and Pregnancy Study Groups criteria. J Clin Endocrinol Metab. 2015; 100(3): 1113-20[DOI][PubMed]
  • 65. Brown KA, Simpson ER. Obesity and breast cancer: mechanisms and therapeutic implications. Front Biosci (Elite Ed). 2012; 4: 2515-24[DOI][PubMed]
  • 66. Rose DP, Gracheck PJ, Vona-Davis L. The Interactions of Obesity, Inflammation and Insulin Resistance in Breast Cancer. Cancers (Basel). 2015; 7(4): 2147-68[DOI][PubMed]
  • 67. Turkoz FP, Solak M, Petekkaya I, Keskin O, Kertmen N, Sarici F, et al. The prognostic impact of obesity on molecular subtypes of breast cancer in premenopausal women. J BUON. 2013; 18(2): 335-41[PubMed]
  • 68. James FR, Wootton S, Jackson A, Wiseman M, Copson ER, Cutress RI. Obesity in breast cancer--what is the risk factor? Eur J Cancer. 2015; 51(6): 705-20[DOI][PubMed]
  • 69. Valladares M, Corsini G, Romero C. [Association between obesity and ovarian cancer]. Rev Med Chil. 2014; 142(5): 593-8[DOI][PubMed]
  • 70. Yang HS, Yoon C, Myung SK, Park SM. Effect of obesity on survival of women with epithelial ovarian cancer: a systematic review and meta-analysis of observational studies. Int J Gynecol Cancer. 2011; 21(9): 1525-32[DOI][PubMed]
  • 71. Sanderson PA, Critchley HO, Williams AR, Arends MJ, Saunders PT. New concepts for an old problem: the diagnosis of endometrial hyperplasia. Hum Reprod Update. 2016; [DOI][PubMed]
  • 72. Wise MR, Jordan V, Lagas A, Showell M, Wong N, Lensen S, et al. Obesity and endometrial hyperplasia and cancer in premenopausal women: A systematic review. Am J Obstet Gynecol. 2016; 214(6): 689 e1-689 e17[DOI][PubMed]
  • 73. Beavis AL, Smith AJ, Fader AN. Lifestyle changes and the risk of developing endometrial and ovarian cancers: opportunities for prevention and management. Int J Womens Health. 2016; 8: 151-67[DOI][PubMed]
  • 74. Dietz WH, Baur LA, Hall K, Puhl RM, Taveras EM, Uauy R, et al. Management of obesity: improvement of health-care training and systems for prevention and care. Lancet. 2015; 385(9986): 2521-33[DOI][PubMed]
  • 75. Reiss K, Breckenkamp J, Borde T, Brenne S, David M, Razum O. Contribution of overweight and obesity to adverse pregnancy outcomes among immigrant and non-immigrant women in Berlin, Germany. Eur J Public Health. 2015; 25(5): 839-44[DOI][PubMed]
  • 76. Ross R, Blair S, de Lannoy L, Despres JP, Lavie CJ. Changing the endpoints for determining effective obesity management. Prog Cardiovasc Dis. 2015; 57(4): 330-6[DOI][PubMed]
  • 77. Spatz DL. Preventing obesity starts with breastfeeding. J Perinat Neonatal Nurs. 2014; 28(1): 41-50[DOI][PubMed]
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