Women’s Health Bulletin

Published by: Kowsar

Non-Occupational Risk Factors for Carpal Tunnel Syndrome: A Review

Marilize C. Burger 1 , Shameemah Abrahams 1 and Malcolm Collins 1 , *
Authors Information
1 Department of Human Biology, University of Cape Town, Cape Town, South Africa
Article information
  • Women's Health Bulletin: March 01, 2016, 3 (2); e34820
  • Published Online: March 27, 2016
  • Article Type: Review Article
  • Received: November 23, 2015
  • Revised: January 18, 2016
  • Accepted: January 18, 2016
  • DOI: 10.17795/whb-34820

To Cite: Burger M C, Abrahams S, Collins M. Non-Occupational Risk Factors for Carpal Tunnel Syndrome: A Review, Women Health Bull. 2016 ; 3(2):e34820. doi: 10.17795/whb-34820.

Abstract
Copyright © 2016, Health Policy Research Center, Shiraz University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Context
2. Evidence Acquisition
3. Results
4. Conclusions
Supplements
Acknowledgements
Footnotes
References
  • 1. Aroori S, Spence RA. Carpal tunnel syndrome. Ulster Med J. 2008; 77(1): 6-17[PubMed]
  • 2. Daniell WE, Fulton-Kehoe D, Chiou LA, Franklin GM. Work-related carpal tunnel syndrome in Washington State workers' compensation: temporal trends, clinical practices, and disability. Am J Ind Med. 2005; 48(4): 259-69[DOI][PubMed]
  • 3. Falkiner S, Myers S. When exactly can carpal tunnel syndrome be considered work-related? ANZ J Surg. 2002; 72(3): 204-9[PubMed]
  • 4. Luckhaupt SE, Dahlhamer JM, Ward BW, Sweeney MH, Sestito JP, Calvert GM. Prevalence and work-relatedness of carpal tunnel syndrome in the working population, United States, 2010 National Health Interview Survey. Am J Ind Med. 2013; 56(6): 615-24[DOI][PubMed]
  • 5. Schulte PA, Lomax G. Assessment of the scientific basis for genetic testing of railroad workers with carpal tunnel syndrome. J Occup Environ Med. 2003; 45(6): 592-600[DOI][PubMed]
  • 6. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009; 6(7)[DOI][PubMed]
  • 7. Dicker RC, Goodman RA, Gregg MB. Field epidemiology. 1996;
  • 8. Verhagen EA, van Mechelen W, de Vente W. The effect of preventive measures on the incidence of ankle sprains. Clin J Sport Med. 2000; 10(4): 291-6
  • 9. Obremskey WT, Pappas N, Attallah-Wasif E, Tornetta P3, Bhandari M. Level of evidence in orthopaedic journals. J Bone Joint Surg Am. 2005; 87(12): 2632-8[DOI][PubMed]
  • 10. Wright JG, Swiontkowski MF, Heckman JD. Introducing levels of evidence to the journal. J Bone Joint Surg. 2003; 85(1): 1-3
  • 11. Posthumus M, Collins M, September AV, Schwellnus MP. The intrinsic risk factors for ACL ruptures: an evidence-based review. Phys Sportsmed. 2011; 39(1): 62-73[DOI][PubMed]
  • 12. Sawaya GF, Guirguis-Blake J, LeFevre M, Harris R, Petitti D, U. S. Preventive Services Task Force . Update on the methods of the U.S. Preventive Services Task Force: estimating certainty and magnitude of net benefit. Ann Intern Med. 2007; 147(12): 871-5[PubMed]
  • 13. Tanaka S, Wild DK, Cameron LL, Freund E. Association of occupational and non-occupational risk factors with the prevalence of self-reported carpal tunnel syndrome in a national survey of the working population. Am J Ind Med. 1997; 32(5): 550-6[PubMed]
  • 14. Tanaka S, Wild DK, Seligman PJ, Halperin WE, Behrens VJ, Putz-Anderson V. Prevalence and work-relatedness of self-reported carpal tunnel syndrome among U.S. workers: analysis of the Occupational Health Supplement data of 1988 National Health Interview Survey. Am J Ind Med. 1995; 27(4): 451-70[PubMed]
  • 15. Sapuan J, Yam KF, Noorman MF, De Cruz PK, Abdul Razab WN, Rozali ZI, et al. Carpal tunnel syndrome in pregnancy - you need to ask! Singapore Med J. 2012; 53(10): 671-5[PubMed]
  • 16. Harris-Adamson C, Eisen EA, Dale AM, Evanoff B, Hegmann KT, Thiese MS, et al. Personal and workplace psychosocial risk factors for carpal tunnel syndrome: a pooled study cohort. Occup Environ Med. 2013; 70(8): 529-37[DOI][PubMed]
  • 17. Gorsche RG, Wiley JP, Renger RF, Brant RF, Gemer TY, Sasyniuk TM. Prevalence and incidence of carpal tunnel syndrome in a meat packing plant. Occup Environ Med. 1999; 56(6): 417-22[PubMed]
  • 18. Nathan PA, Meadows KD, Istvan JA. Predictors of carpal tunnel syndrome: an 11-year study of industrial workers. J Hand Surg Am. 2002; 27(4): 644-51[PubMed]
  • 19. Bonfiglioli R, Mattioli S, Armstrong TJ, Graziosi F, Marinelli F, Farioli A, et al. Validation of the ACGIH TLV for hand activity level in the OCTOPUS cohort: a two-year longitudinal study of carpal tunnel syndrome. Scand J Work Environ Health. 2013; 39(2): 155-63[DOI][PubMed]
  • 20. Wolf JM, Mountcastle S, Owens BD. Incidence of carpal tunnel syndrome in the US military population. Hand (N Y). 2009; 4(3): 289-93[DOI][PubMed]
  • 21. Violante FS, Armstrong TJ, Fiorentini C, Graziosi F, Risi A, Venturi S, et al. Carpal tunnel syndrome and manual work: a longitudinal study. J Occup Environ Med. 2007; 49(11): 1189-96[DOI][PubMed]
  • 22. Petit A, Ha C, Bodin J, Rigouin P, Descatha A, Brunet R, et al. Risk factors for carpal tunnel syndrome related to the work organization: a prospective surveillance study in a large working population. Appl Ergon. 2015; 47: 1-10[DOI][PubMed]
  • 23. Roh YH, Chung MS, Baek GH, Lee YH, Rhee SH, Gong HS. Incidence of clinically diagnosed and surgically treated carpal tunnel syndrome in Korea. J Hand Surg Am. 2010; 35(9): 1410-7[DOI][PubMed]
  • 24. Moghtaderi A, Izadi S, Sharafadinzadeh N. An evaluation of gender, body mass index, wrist circumference and wrist ratio as independent risk factors for carpal tunnel syndrome. Acta Neurol Scand. 2005; 112(6): 375-9[DOI][PubMed]
  • 25. Chiang HC, Ko YC, Chen SS, Yu HS, Wu TN, Chang PY. Prevalence of shoulder and upper-limb disorders among workers in the fish-processing industry. Scand J Work Environ Health. 1993; 19(2): 126-31[PubMed]
  • 26. Tseng CH, Liao CC, Kuo CM, Sung FC, Hsieh DP, Tsai CH. Medical and non-medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million. Eur J Neurol. 2012; 19(1): 91-7[DOI][PubMed]
  • 27. Eleftheriou A, Rachiotis G, Varitimidis SE, Koutis C, Malizos KN, Hadjichristodoulou C. Cumulative keyboard strokes: a possible risk factor for carpal tunnel syndrome. J Occup Med Toxicol. 2012; 7(1): 16[DOI][PubMed]
  • 28. Armstrong T, Dale AM, Franzblau A, Evanoff BA. Risk factors for carpal tunnel syndrome and median neuropathy in a working population. J Occup Environ Med. 2008; 50(12): 1355-64[DOI][PubMed]
  • 29. Solomon DH, Katz JN, Bohn R, Mogun H, Avorn J. Nonoccupational risk factors for carpal tunnel syndrome. J Gen Intern Med. 1999; 14(5): 310-4[PubMed]
  • 30. Maghsoudipour M, Moghimi S, Dehghaan F, Rahimpanah A. Association of occupational and non-occupational risk factors with the prevalence of work related carpal tunnel syndrome. J Occup Rehabil. 2008; 18(2): 152-6[DOI][PubMed]
  • 31. Jianmongkol S, Kosuwon W, Thumroj E, Sumanont S. Prevalence of carpal tunnel syndrome in workers from a fishnet factory in Thailand. Hand Surg. 2005; 10(1): 67-70[DOI][PubMed]
  • 32. Raman SR, Al-Halabi B, Hamdan E, Landry MD. Prevalence and risk factors associated with self-reported carpal tunnel syndrome (CTS) among office workers in Kuwait. BMC Res Notes. 2012; 5: 289[DOI][PubMed]
  • 33. Becker J, Nora DB, Gomes I, Stringari FF, Seitensus R, Panosso JS, et al. An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome. Clin Neurophysiol. 2002; 113(9): 1429-34[PubMed]
  • 34. Burt S, Crombie K, Jin Y, Wurzelbacher S, Ramsey J, Deddens J. Workplace and individual risk factors for carpal tunnel syndrome. Occup Environ Med. 2011; 68(12): 928-33[DOI][PubMed]
  • 35. Estirado de Cabo E, Posada de la Paz M, de Andres Copa P, Plaza Cano Mdel M, Garcia de Aguinaga ML, Suarez Alvarez C, et al. Carpal tunnel syndrome. A new feature in the natural history of TOS? Eur J Epidemiol. 2003; 18(10): 983-93[PubMed]
  • 36. Kiani J, Goharifar H, Moghimbeigi A, Azizkhani H. Prevalence and risk factors of five most common upper extremity disorders in diabetics. J Res Health Sci. 2014; 14(1): 92-5[PubMed]
  • 37. Garg A, Kapellusch J, Hegmann K, Wertsch J, Merryweather A, Deckow-Schaefer G, et al. The Strain Index (SI) and Threshold Limit Value (TLV) for Hand Activity Level (HAL): risk of carpal tunnel syndrome (CTS) in a prospective cohort. Ergonomics. 2012; 55(4): 396-414[DOI][PubMed]
  • 38. Roquelaure Y, Mariel J, Dano C, Fanello S, Penneau-Fontbonne D. Prevalence, incidence and risk factors of carpal tunnel syndrome in a large footwear factory. Int J Occup Med Environ Health. 2001; 14(4): 357-67[PubMed]
  • 39. Werner RA, Franzblau A, Gell N, Hartigan AG, Ebersole M, Armstrong TJ. Incidence of carpal tunnel syndrome among automobile assembly workers and assessment of risk factors. J Occup Environ Med. 2005; 47(10): 1044-50[PubMed]
  • 40. Cartwright MS, Walker FO, Newman JC, Schulz MR, Arcury TA, Grzywacz JG, et al. One-year incidence of carpal tunnel syndrome in Latino poultry processing workers and other Latino manual workers. Am J Ind Med. 2014; 57(3): 362-9[DOI][PubMed]
  • 41. Dale AM, Gardner BT, Zeringue A, Strickland J, Descatha A, Franzblau A, et al. Self-reported physical work exposures and incident carpal tunnel syndrome. Am J Ind Med. 2014; 57(11): 1246-54[DOI][PubMed]
  • 42. Frost P, Andersen JH, Nielsen VK. Occurrence of carpal tunnel syndrome among slaughterhouse workers. Scand J Work Environ Health. 1998; 24(4): 285-92[PubMed]
  • 43. Latko WA, Armstrong TJ, Franzblau A, Ulin SS, Werner RA, Albers JW. Cross-sectional study of the relationship between repetitive work and the prevalence of upper limb musculoskeletal disorders. Am J Ind Med. 1999; 36(2): 248-59[PubMed]
  • 44. Silverstein B, Fan ZJ, Smith CK, Bao S, Howard N, Spielholz P, et al. Gender adjustment or stratification in discerning upper extremity musculoskeletal disorder risk? Scand J Work Environ Health. 2009; 35(2): 113-26[PubMed]
  • 45. Atroshi I, Gummesson C, Ornstein E, Johnsson R, Ranstam J. Carpal tunnel syndrome and keyboard use at work: a population-based study. Arthritis Rheum. 2007; 56(11): 3620-5[DOI][PubMed]
  • 46. Bland JD. The relationship of obesity, age, and carpal tunnel syndrome: more complex than was thought? Muscle Nerve. 2005; 32(4): 527-32[DOI][PubMed]
  • 47. Conlon CF, Rempel DM. Upper extremity mononeuropathy among engineers. J Occup Environ Med. 2005; 47(12): 1276-84[PubMed]
  • 48. Leclerc A, Franchi P, Cristofari MF, Delemotte B, Mereau P, Teyssier-Cotte C, et al. Carpal tunnel syndrome and work organisation in repetitive work: a cross sectional study in France. Study Group on Repetitive Work. Occup Environ Med. 1998; 55(3): 180-7[PubMed]
  • 49. Cartwright MS, Walker FO, Blocker JN, Schulz MR, Arcury TA, Grzywacz JG, et al. The prevalence of carpal tunnel syndrome in Latino poultry-processing workers and other Latino manual workers. J Occup Environ Med. 2012; 54(2): 198-201[DOI][PubMed]
  • 50. Hendriks SH, van Dijk PR, Groenier KH, Houpt P, Bilo HJ, Kleefstra N. Type 2 diabetes seems not to be a risk factor for the carpal tunnel syndrome: a case control study. BMC Musculoskelet Disord. 2014; 15: 346[DOI][PubMed]
  • 51. Sestak I, Sapunar F, Cuzick J. Aromatase inhibitor-induced carpal tunnel syndrome: results from the ATAC trial. J Clin Oncol. 2009; 27(30): 4961-5[DOI][PubMed]
  • 52. Mieog JS, Morden JP, Bliss JM, Coombes RC, van de Velde CJ, I. E. S. Steering Committee . Carpal tunnel syndrome and musculoskeletal symptoms in postmenopausal women with early breast cancer treated with exemestane or tamoxifen after 2-3 years of tamoxifen: a retrospective analysis of the Intergroup Exemestane Study. Lancet Oncol. 2012; 13(4): 420-32[DOI][PubMed]
  • 53. Leclerc A, Landre MF, Chastang JF, Niedhammer I, Roquelaure Y, Study Group on Repetitive W. Upper-limb disorders in repetitive work. Scand J Work Environ Health. 2001; 27(4): 268-78[PubMed]
  • 54. Mattioli S, Baldasseroni A, Bovenzi M, Curti S, Cooke RM, Campo G, et al. Risk factors for operated carpal tunnel syndrome: a multicenter population-based case-control study. BMC Public Health. 2009; 9: 343[DOI][PubMed]
  • 55. de Krom MC, Kester AD, Knipschild PG, Spaans F. Risk factors for carpal tunnel syndrome. Am J Epidemiol. 1990; 132(6): 1102-10[PubMed]
  • 56. Mondelli M, Aretini A, Ginanneschi F, Greco G, Mattioli S. Waist circumference and waist-to-hip ratio in carpal tunnel syndrome: a case-control study. J Neurol Sci. 2014; 338(1-2): 207-13[DOI][PubMed]
  • 57. Ferry S, Hannaford P, Warskyj M, Lewis M, Croft P. Carpal tunnel syndrome: a nested case-control study of risk factors in women. Am J Epidemiol. 2000; 151(6): 566-74[PubMed]
  • 58. Burt S, Deddens JA, Crombie K, Jin Y, Wurzelbacher S, Ramsey J. A prospective study of carpal tunnel syndrome: workplace and individual risk factors. Occup Environ Med. 2013; 70(8): 568-74[DOI][PubMed]
  • 59. Gell N, Werner RA, Franzblau A, Ulin SS, Armstrong TJ. A longitudinal study of industrial and clerical workers: incidence of carpal tunnel syndrome and assessment of risk factors. J Occup Rehabil. 2005; 15(1): 47-55[PubMed]
  • 60. Fung BK, Chan KY, Lam LY, Cheung SY, Choy NK, Chu KW, et al. Study of wrist posture, loading and repetitive motion as risk factors for developing carpal tunnel syndrome. Hand Surg. 2007; 12(1): 13-8[DOI][PubMed]
  • 61. Shiri R, Heliovaara M, Moilanen L, Viikari J, Liira H, Viikari-Juntura E. Associations of cardiovascular risk factors, carotid intima-media thickness and manifest atherosclerotic vascular disease with carpal tunnel syndrome. BMC Musculoskelet Disord. 2011; 12: 80[DOI][PubMed]
  • 62. Lozano-Calderon S, Anthony S, Ring D. The quality and strength of evidence for etiology: example of carpal tunnel syndrome. J Hand Surg Am. 2008; 33(4): 525-38[DOI][PubMed]
  • 63. McCartan B, Ashby E, Taylor EJ, Haddad FS. Carpal tunnel syndrome. Br J Hospital Med. 2012; 73(4): 199-202[DOI]
  • 64. Hlebs S, Majhenic K, Vidmar G. Body mass index and anthropometric characteristics of the hand as risk factors for carpal tunnel syndrome. Coll Antropol. 2014; 38(1): 219-26[PubMed]
  • 65. Boz C, Ozmenoglu M, Altunayoglu V, Velioglu S, Alioglu Z. Individual risk factors for carpal tunnel syndrome: an evaluation of body mass index, wrist index and hand anthropometric measurements. Clin Neurol Neurosurg. 2004; 106(4): 294-9[DOI][PubMed]
  • 66. Kouyoumdjian JA, Zanetta DM, Morita MP. Evaluation of age, body mass index, and wrist index as risk factors for carpal tunnel syndrome severity. Muscle Nerve. 2002; 25(1): 93-7[PubMed]
  • 67. Vogelin E, Meszaros T, Schoni F, Constantinescu MA. Sonographic wrist measurements and detection of anatomical features in carpal tunnel syndrome. ScientificWorldJournal. 2014; 2014: 657906[DOI][PubMed]
  • 68. Hemminki K, Li X, Sundquist K. Familial risks for nerve, nerve root and plexus disorders in siblings based on hospitalisations in Sweden. J Epidemiol Community Health. 2007; 61(1): 80-4[DOI][PubMed]
  • 69. Bonfiglioli R, Mattioli S, Fiorentini C, Graziosi F, Curti S, Violante FS. Relationship between repetitive work and the prevalence of carpal tunnel syndrome in part-time and full-time female supermarket cashiers: a quasi-experimental study. Int Arch Occup Environ Health. 2007; 80(3): 248-53[DOI][PubMed]
  • 70. Nordstrom DL, Vierkant RA, DeStefano F, Layde PM. Risk factors for carpal tunnel syndrome in a general population. Occup Environ Med. 1997; 54(10): 734-40[PubMed]
  • 71. Burger M, de Wet H, Collins M. The COL5A1 gene is associated with increased risk of carpal tunnel syndrome. Clin Rheumatol. 2015; 34(4): 767-74[DOI][PubMed]
  • 72. Burger MC, De Wet H, Collins M. The BGN and ACAN genes and carpal tunnel syndrome. Gene. 2014; 551(2): 160-6[DOI][PubMed]
  • 73. Burger MC, de Wet H, Collins M. Interleukin and growth factor gene variants and risk of carpal tunnel syndrome. Gene. 2015; 564(1): 67-72[DOI][PubMed]
  • 74. Eroglu P, Erkol Inal E, Sag SO, Gorukmez O, Topak A, Yakut T. Associations analysis of GSTM1, T1 and P1 Ile105Val polymorphisms with carpal tunnel syndrome. Clin Rheumatol. 2015; [DOI][PubMed]
  • 75. Hakim AJ, Cherkas L, El Zayat S, MacGregor AJ, Spector TD. The genetic contribution to carpal tunnel syndrome in women: a twin study. Arthritis Rheum. 2002; 47(3): 275-9[DOI][PubMed]
  • 76. Coggon D, Ntani G, Harris EC, Linaker C, Van der Star R, Cooper C, et al. Differences in risk factors for neurophysiologically confirmed carpal tunnel syndrome and illness with similar symptoms but normal median nerve function: a case-control study. BMC Musculoskelet Disord. 2013; 14: 240[DOI][PubMed]
  • 77. Ali KM, Sathiyasekaran BW. Computer professionals and Carpal Tunnel Syndrome (CTS). Int J Occup Saf Ergon. 2006; 12(3): 319-25[PubMed]
  • 78. Yagev Y, Gringolds M, Karakis I, Carel RS. Carpal tunnel syndrome: under-recognition of occupational risk factors by clinicians. Ind Health. 2007; 45(6): 820-2[PubMed]
  • 79. Anton D, Rosecrance J, Merlino L, Cook T. Prevalence of musculoskeletal symptoms and carpal tunnel syndrome among dental hygienists. Am J Ind Med. 2002; 42(3): 248-57[DOI][PubMed]
  • 80. Mondelli M, Grippo A, Mariani M, Baldasseroni A, Ansuini R, Ballerini M, et al. Carpal tunnel syndrome and ulnar neuropathy at the elbow in floor cleaners. Neurophysiol Clin. 2006; 36(4): 245-53[DOI][PubMed]
  • 81. Geoghegan JM, Clark DI, Bainbridge LC, Smith C, Hubbard R. Risk factors in carpal tunnel syndrome. J Hand Surg Br. 2004; 29(4): 315-20[DOI][PubMed]
  • 82. Morgenstern H, Kelsh M, Kraus J, Margolis W. A cross-sectional study of hand/wrist symptoms in female grocery checkers. Am J Ind Med. 1991; 20(2): 209-18[PubMed]
  • 83. Wessel LE, Fufa DT, Boyer MI, Calfee RP. Epidemiology of carpal tunnel syndrome in patients with single versus multiple trigger digits. J Hand Surg Am. 2013; 38(1): 49-55[DOI][PubMed]
  • 84. Awada A, Amene P, Abdulrazak M, Obeid T. Carpal Tunnel Syndrome: A prospective clinical study of one hundred cases. Saudi Med J. 1998; 19(2): 166-9
  • 85. Sekijima Y, Uchiyama S, Tojo K, Sano K, Shimizu Y, Imaeda T, et al. High prevalence of wild-type transthyretin deposition in patients with idiopathic carpal tunnel syndrome: a common cause of carpal tunnel syndrome in the elderly. Hum Pathol. 2011; 42(11): 1785-91[DOI][PubMed]
  • 86. Sousa Vasconcelos JT, Freitas Paiva AM, Cavalcanti MF, de Carvalho JF, Bonfa E, Borba EF. Carpal tunnel syndrome and prediabetes: is there a true association? Clin Neurol Neurosurg. 2015; 137: 57-61[DOI][PubMed]
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