Women’s Health Bulletin

Published by: Kowsar

Protective Effects of Aerobic Intervention on the Profile of Liver Enzymes with Emphasis on AST to ALT ratio in Adult Females with Obesity

Maryam Farbod 1 , Mojtaba Eizadi 2 , * and Sakineh Davoodzadeh 3
Authors Information
1 Department of Physical Education and Sport Sciences, Parand Branch, Islamic Azad University, Tehran, Iran
2 Department of Exercise Physiology, Saveh Branch, Islamic Azad University, Saveh, Iran
3 Department of Exercise Physiology, College of Physical Education and Sport Sciences, Tehran University, Tehran, Iran
Article information
  • Women’s Health Bulletin: October 2018, 5 (4); e57194
  • Published Online: June 25, 2018
  • Article Type: Research Article
  • Received: July 10, 2017
  • Revised: February 27, 2018
  • Accepted: February 28, 2018
  • DOI: 10.5812/whb.57194

To Cite: Farbod M, Eizadi M, Davoodzadeh S. Protective Effects of Aerobic Intervention on the Profile of Liver Enzymes with Emphasis on AST to ALT ratio in Adult Females with Obesity, Women Health Bull. 2018 ; 5(4):e57194. doi: 10.5812/whb.57194.

Abstract
Copyright © 2018, Women’s Health Bulletin. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnote
References
  • 1. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346(6):393-403. doi: 10.1056/NEJMoa012512. [PubMed: 11832527]. [PubMed Central: PMC1370926].
  • 2. Den Longo D. Principle of Internal Medicine; Disorders of the Liver & Billiary Disease. 18 ed. 2012.
  • 3. Das SK, Balakrishnan V. Role of cytokines in the pathogenesis of non-alcoholic Fatty liver disease. Indian J Clin Biochem. 2011;26(2):202-9. doi: 10.1007/s12291-011-0121-7. [PubMed: 22468051]. [PubMed Central: PMC3107419].
  • 4. Jamali R, Khonsari M, Merat S, Khoshnia M, Jafari E, Bahram Kalhori A, et al. Persistent alanine aminotransferase elevation among the general Iranian population: prevalence and causes. World J Gastroenterol. 2008;14(18):2867-71. doi: 10.3748/wjg.14.2867. [PubMed: 18473412]. [PubMed Central: PMC2710729].
  • 5. Wong VW, Vergniol J, Wong GL, Foucher J, Chan HL, Le Bail B, et al. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology. 2010;51(2):454-62. doi: 10.1002/hep.23312. [PubMed: 20101745].
  • 6. Nobili V, Alisi A, Vania A, Tiribelli C, Pietrobattista A, Bedogni G. The pediatric NAFLD fibrosis index: a predictor of liver fibrosis in children with non-alcoholic fatty liver disease. BMC Med. 2009;7:21. doi: 10.1186/1741-7015-7-21. [PubMed: 19409076]. [PubMed Central: PMC2684116].
  • 7. Fan JG, Zhu J, Li XJ, Chen L, Li L, Dai F, et al. Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J Hepatol. 2005;43(3):508-14. doi: 10.1016/j.jhep.2005.02.042. [PubMed: 16006003].
  • 8. Ordonez FJ, Rosety MA, Camacho A, Rosety I, Diaz AJ, Fornieles G, et al. Aerobic training improved low-grade inflammation in obese women with intellectual disability. J Intellect Disabil Res. 2014;58(6):583-90. doi: 10.1111/jir.12056. [PubMed: 23742222].
  • 9. Donges CE, Duffield R, Guelfi KJ, Smith GC, Adams DR, Edge JA. Comparative effects of single-mode vs. duration-matched concurrent exercise training on body composition, low-grade inflammation, and glucose regulation in sedentary, overweight, middle-aged men. Appl Physiol Nutr Metab. 2013;38(7):779-88. doi: 10.1139/apnm-2012-0443. [PubMed: 23980737].
  • 10. Olson TP, Dengel DR, Leon AS, Schmitz KH. Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women. Int J Obes (Lond). 2007;31(6):996-1003. doi: 10.1038/sj.ijo.0803534. [PubMed: 17299382].
  • 11. Lebon J, Riesco E, Tessier D, Dionne IJ. Additive effects of isoflavones and exercise training on inflammatory cytokines and body composition in overweight and obese postmenopausal women: a randomized controlled trial. Menopause. 2014;21(8):869-75. doi: 10.1097/GME.0000000000000177. [PubMed: 24378766].
  • 12. Hallsworth K, Fattakhova G, Hollingsworth KG, Thoma C, Moore S, Taylor R, et al. Resistance exercise reduces liver fat and its mediators in non-alcoholic fatty liver disease independent of weight loss. Gut. 2011;60(9):1278-83. doi: 10.1136/gut.2011.242073. [PubMed: 21708823]. [PubMed Central: PMC3152868].
  • 13. Kawanishi N, Yano H, Mizokami T, Takahashi M, Oyanagi E, Suzuki K. Exercise training attenuates hepatic inflammation, fibrosis and macrophage infiltration during diet induced-obesity in mice. Brain Behav Immun. 2012;26(6):931-41. doi: 10.1016/j.bbi.2012.04.006. [PubMed: 22554494].
  • 14. Slentz CA, Bateman LA, Willis LH, Shields AT, Tanner CJ, Piner LW, et al. Effects of aerobic vs. resistance training on visceral and liver fat stores, liver enzymes, and insulin resistance by HOMA in overweight adults from STRRIDE AT/RT. Am J Physiol Endocrinol Metab. 2011;301(5):E1033-9. doi: 10.1152/ajpendo.00291.2011. [PubMed: 21846904]. [PubMed Central: PMC3214001].
  • 15. Devries MC, Samjoo IA, Hamadeh MJ, Tarnopolsky MA. Effect of endurance exercise on hepatic lipid content, enzymes, and adiposity in men and women. Obesity (Silver Spring). 2008;16(10):2281-8. doi: 10.1038/oby.2008.358. [PubMed: 18719669].
  • 16. Barani F, Afzalpour ME, Ilbiegi S, Kazemi T, Mohammadi Fard M. [The effect of resistance and combined exercise on serum levels of the liver enzymes and fitness indicators in nonalcoholic women with fatty liver]. J Birjand Univ Med Sci. 2014;21(2):188-202. Persian.
  • 17. Bemben DA, Palmer IJ, Abe T, Sato Y, Bemben MG. Effects of a single bout of low intensity KAATSU resistance training on markers of bone turnover in young men. Int J KAATSU Train Res. 2007;3(2):21-6. doi: 10.3806/ijktr.3.21.
  • 18. Barzegarzadeh-Zarandi H, Dabidy-Roshan V. [Changes in some liver enzymes and blood lipid level following interval and continuous regular aerobic training in old rats]. Journal of Shahrekord University of Medical Sciences. 2012;14(5):13-23. Persian.
  • 19. Tartibian B, Moutab Saei N. [Effects of 9-weeks high intensity aerobic exercises on parathyroid hormone and marker of metabolism of bone formation in young women]. Olympic. 2009;16(4):79-88. Persian.
  • 20. Khorshidi D, Matinhomaee H, Azarbayjani MA, Hossein-Nezhad A. [Effect of One Period of Aerobic Exercise on Serum Levels of Alkaline Phosphatase and Osteocalcin in Patients with Type 2 Diabetes]. J Shahid Sadoghi Univ Med Sci. 2011;15(5):676-85. Persian.
  • 21. Bijeh N, Rashidlamir AR, Sadeghynia S, Hejazi K. The effect of eight weeks swimming training on hepatic enzymes and hematological values in young female. Int J Basic Sci Appl Res. 2013;2(1):123-8.
  • 22. de Piano A, Prado WL, Caranti DA, Siqueira KO, Stella SG, Lofrano M, et al. Metabolic and nutritional profile of obese adolescents with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2007;44(4):446-52. doi: 10.1097/MPG.0b013e31803815d9. [PubMed: 17414142].
  • 23. Reddy JK, Rao MS. Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. Am J Physiol Gastrointest Liver Physiol. 2006;290(5):G852-8. doi: 10.1152/ajpgi.00521.2005. [PubMed: 16603729].
  • 24. Bahari S, Faramarzi M, Azamian JA, Cheragh CM. The effect of 8 week resistance training on resting level of liver inflammatory markers and insulin resistance of type 2 diabetic women. Armaghane-Danesh Yasuj Univ Med Sci J. 2014;19(88):450-61.
  • 25. Straznicky NE, Lambert EA, Grima MT, Eikelis N, Nestel PJ, Dawood T, et al. The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects. Diabetes Obes Metab. 2012;14(2):139-48. doi: 10.1111/j.1463-1326.2011.01497.x. [PubMed: 21923735].
  • 26. Omagari K, Kadokawa Y, Masuda J, Egawa I, Sawa T, Hazama H, et al. Fatty liver in non-alcoholic non-overweight Japanese adults: incidence and clinical characteristics. J Gastroenterol Hepatol. 2002;17(10):1098-105. doi: 10.1046/j.1440-1746.2002.02846.x. [PubMed: 12201871].
  • 27. Burtis C, Ashwood E, Bruns DE. [Clinical Biochemistry Tietz: analyte and Pathophysiology]. 1st ed. Tehran: Ketab Arjmand publication; 2011. p. 125-600. Persian.
  • 28. Rodriguez B, Torres DM, Harrison SA. Physical activity: an essential component of lifestyle modification in NAFLD. Nat Rev Gastroenterol Hepatol. 2012;9(12):726-31. doi: 10.1038/nrgastro.2012.200. [PubMed: 23090329].
  • 29. Pettersson J, Hindorf U, Persson P, Bengtsson T, Malmqvist U, Werkstrom V, et al. Muscular exercise can cause highly pathological liver function tests in healthy men. Br J Clin Pharmacol. 2008;65(2):253-9. doi: 10.1111/j.1365-2125.2007.03001.x. [PubMed: 17764474]. [PubMed Central: PMC2291230].
  • 30. Hershberger AM, McCammon MR, Garry JP, Mahar MT, Hickner RC. Responses of lipolysis and salivary cortisol to food intake and physical activity in lean and obese children. J Clin Endocrinol Metab. 2004;89(9):4701-7. doi: 10.1210/jc.2003-031144. [PubMed: 15356083].
  • 31. Fraser A, Harris R, Sattar N, Ebrahim S, Davey Smith G, Lawlor DA. Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis. Diabetes Care. 2009;32(4):741-50. doi: 10.2337/dc08-1870. [PubMed: 19131466]. [PubMed Central: PMC2660465].
  • 32. Grundy SM. Gamma-glutamyl transferase: another biomarker for metabolic syndrome and cardiovascular risk. Arterioscler Thromb Vasc Biol. 2007;27(1):4-7. doi: 10.1161/01.ATV.0000253905.13219.4b. [PubMed: 17185620].
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