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If you have symptoms such as irregular bowel movements, rectal bleeding, excessive heartburn, stomach pain, bloating, or difficulty swallowing, you might be advised to see a gastroenterologist, a digestive disorders specialist, or if you are of age to begin routine colorectal cancer screening.

If your symptoms are fresh or mild in severity, you can see your regular doctor for some preliminary tests. He or she will decide whether or not you need to see a specialist.

Author: Dr. Sarmed Sami MBChB, MRCP, PGCME, PhD

Consultant Gastroenterologist, Founder and Director of Digestive Health UK. https://digestivehealthuk.com/

Who is a gastroenterologist?

Many people think of the human gastrointestinal system as consisting only of the stomach and intestines. The oesophagus, stomach, small intestine, colon, and rectum, as well as the pancreas, gallbladder, bile ducts, and liver, are all examined in gastroenterology.

Abnormal bowel movements

Constipation can be caused by a blockage, neurological problems, muscular or hormonal dysfunction, diet, or other causes if you have less than three bowel movements per week. A gastroenterologist will help you figure out what’s causing your symptoms.

Diarrhea: If you have runny stool for more than a few days, it may be caused by a virus, parasite/bacteria, lactose sensitivity, a drug reaction, or other digestive disorders like Crohn’s disease or ulcerative colitis, to name a few.

Rectal bleeding

Blood in the stool may have a variety of causes, but it usually indicates that there is bleeding somewhere in your digestive tract. An anal fissure (a minor cut or tear in the tissue lining the anus), haemorrhoids, or anything needing medical treatment, such as cancer, may be the cause.

Heartburn

Heartburn on rare occasions is probably nothing to worry about, but chronic heartburn could mean GERD, Barrett’s Esophagus, or even esophageal cancer. If you have frequent acid reflux, you could be diagnosed with GERD and given medication to relieve your pain, as well as tests to validate the diagnosis.

45 plus age

A screening test is a preventative measure that should be performed prior to the onset of symptoms. Precancerous polyps, which can be detected and removed during a colonoscopy, are also the start of colorectal cancer. Adults aged 50 to 75 should be screened for colorectal cancer, according to the United States Preventive Services Task Force (USPSTF). Some patients need screening colonoscopies sooner than others. African Americans, for example, should begin the screening process at the age of 45.

Conclusion

You may have trouble swallowing or are unable to swallow due to some illnesses. If you have frequent esophageal pain or trouble swallowing, or if your difficulty swallowing worsens over time, a gastroenterologist can perform an upper endoscopy to determine the source of your discomfort and begin treating it.

Many men have a hard time talking about erectile dysfunction, or ED, often because it relates to their masculinity. In simple words, erectile dysfunction is a condition, where a man has a hard time getting or maintaining an erection. Occasional issues with erection, however, doesn’t mean that a man has erectile dysfunction. If you believe you have ED, you should consider seeing an experienced urologist Brooklyn New York. Urologists are trained to treat problems of the male reproductive system, including ED. 

Symptoms

The most common symptom of erectile dysfunction (ED) is inability to get an erection, or retaining the erection long enough for penetrative sex. Contrary to what many men believe, erectile dysfunction is not that uncommon and can affect a man at any age. Like we mentioned, just because you couldn’t get an erection once or a few times, it doesn’t mean you have erectile dysfunction that cannot be treated. 

Causes

There are several causes of erectile dysfunction, including diabetes, high blood pressure, kidney disease, low testosterone levels, hormonal imbalance, stress, anxiety, depression, and relationship problems. Some medications taken for specific health problems may also contribute to erectile dysfunction. Health conditions, including Parkinson’s disease, and habits like smoking or tobacco use have been associated with ED. 

Treatment 

ED treatment usually depends on the underlying cause. A urologist is the best person to decide on the course of the treatment. Medications that can improve blood flow to the penis, such as Viagra or Stendra, can be recommended to some patients. Other treatments like Testosterone therapy (TRT) and penile implant may be recommended, as well. Since psychological factors can cause ED, talk therapy is also used at times. There are also exercises that can help in reducing ED. 

Seeing a urologist

If you have any of the signs and symptoms listed above, or reduced interest in sex, consider seeing a urologist. While ED may seem like a serious problem, it is not always so, and in some cases, just talk therapy and a few lifestyle changes can help. Talking to a urologist is extremely easy, and most urologists prefer to maintain a professional stance towards the problem. In some cases, they may even recommend a few additional tests, so that the actual problem can be found. 

With the right urologist, you can expect to see a difference in your ED symptoms in no time – Just do not ignore the early signs. 

 

 

Peptides or polypeptides are a small chain of amino acid, which triggers human growth hormone or other naturally occurring hormones that control physical changes in a body. We are very well aware of the fact that peptides are commonly used for bodybuilding or anti-aging purposes. However, there are multiple other uses of peptides for the human body, if taken under the controlled measure. Peptides naturally occur in the skin and when there is some deficiency of certain proteins they take the role to balance it. Collagen, which is made up of 3 polypeptide chains, leads to better and repaired skin, thus makes you look younger.

Why is collagen required?

The need for collagen in the body is supplied by the body itself, but over time the production lowers down. In such a situation, wrinkles and fine lines appear on the skin and make it look aged. The proper consumption of the application of peptide-based medication can heal your skin and retain its natural condition. You can buy peptides from specific stores or buy Receptor Grade IGF-1 LR3 Online, which is mainly used for cell proliferation or cell-division, but also used for structural changes.

Improves skin 

Skin normally prevents bacteria, fungus, toxins, pollution, or ultraviolet ray to affect the body. The skin works as a shield to play a defensive role for and peptides help in enhancing this character. Skin absorbs peptides when it is needed and thus ensures a safer and healthier human body.

Anti-aging characteristic 

These peptides help in making the skin firmer and healthier. And as a result, it reduces wrinkles and fine lines, which are visible from the outside. Also, the collagen helps in making the skin more elastic and less damage-prone.

The anti-microbial approach also helps a skin to retain its natural beauty by killing the bacteria that can cause acne.

The function of peptides on skin

Usually, peptides are present in the body for the natural growth of the body and healing damages. However, with time peptides need to be pushed into the body, under medical supervision, so that the peptides can play as a catalyst. The peptides go inside the skin layers and send messages to cells for producing collagen.

 

One should follow some scientific method in the process of selection of peptides. It will be difficult to start your search, thus you need to have good knowledge of the product. Physicians can help you in the process. It is also strictly mentioned that peptides should not be consumed or applied without the consent of a doctor. Peptides can have an adverse impact if taken at a higher concentration or if the person has some prolong ailment. Pregnant women should stay away from peptides at any condition. Skincare products use peptides for formulating a drug so always go for branded products. Peptide application or consumption can lead to an allergic reaction and thus it should be used very carefully. Still, now research work is going on to deliver further scientific advantages of peptides for a human trial. 

 

Hereditary fructose intolerance is an autosomal recessive congenital disorder caused by mutation in the gene encoding the synthesis of the type B aldolase enzyme, located on chromosome 9q31.1. This mutation reduces the enzymatic activity of type B aldolase, expressed mainly in the liver, but which can also be found in intestinal and renal cells. The role of aldolase is to cleave phosphorylated fructose (fructose-1-phosphate) into glyceraldehyde and dihydroxyacetone phosphate. Thus the body’s ability to metabolize fructose is dramatically affected, resulting in the accumulation of fructose in liver cells in the form of fructose-1-phosphate.

The Right Accumulation

The accumulation of fructose-1-phosphate in the hepatocyte cytoplasm leads to the sequential sequestration of inorganic phosphate and the activation of adenosine monophosphate (AMP) deaminase which irreversibly catalyzes the deamination of AMP to IMP (inosine monophosphate) and adenine is converted to uric acid. Nicotinamide Mononucleotide or NMN is from the nucleotides family. The nucleotides are those organic modules that are found in maximum food items that we consume. Along with the other nucleotides The NMN happens to be made of 3 parts. In simpler words, the higher the NMN is, the higher is the level of NAD+. Choosing the right nmn powder manufacturer is important in this case.

The Right Ratio

Consequently, the ratio between AMP and adenosine triphosphate (ATP) changes dramatically, the tissue depletion of ATP being a consequence of the massive degradation of uric acid and the impossibility of regenerating ATP reserves (the process of oxidative phosphorylation in mitochondria – cell power plants- cannot occur in the absence of inorganic phosphate, which is sequestered in the cytoplasm). Low availability of ATP in liver tissue affects gluconeogenesis (causing hypoglycemia and vomiting) and protein synthesis (causing a reduction in the production of clotting factors and other proteins vital to the body).

  • The inability of fructose to be cleaved into glyceraldehyde and dihydroxyacetonphosphate, which participates in the processes of glycolysis and gluconeogenesis, disrupts the homeostasis of carbohydrate metabolism. This explains the hypoglycemia and metabolic acidosis that accompany hereditary fructose intolerance. Intense degradation of uric acid Explain could clinically impaired hyperuricemic. Also, the competition between urate and lactate for renal excretion is considered responsible for the occurrence oflactic acidosis.
  • Another consequence of increased fructose-1-phosphate concentrations is the inhibition of fructokinase by a feedback mechanism, causing an increase in the level of free fructose in the blood (fructose).
  • Intracellular accumulation of fructose-1-phosphate may induce hepatocellular toxicity , which may be one of the mechanisms responsible for severe liver dysfunction / destruction. The onset of proximal renal tubulopathy is not a well-defined cause, but it can often be complicated by amino acids, glucosuria, phosphaturia, and bicarbonate.

Conclusion

The prevalence of hereditary fructose intolerance is unknown, but some studies in the United States and Europe estimate its frequency in 1 in 20,000 newborns, respectively 12,000 – 58,000 births according to an analysis conducted. For fighting against different diseases, the use of the NAD+ form happens to be of the best importance. Just like the NMN powder, the NR powder is also quite effective. In the elevation of the NAD+ levels, that faces decline as the age increases, both of these powers are used for a number of physical ailments. But other than that the NR powder and the NMN powder is also available now that work as perfect supplement options. You can choose the best nr powder manufacturer for the same.

The introduction of artificial intelligence (AI) systems in medicine is one of the most important modern trends in world healthcare. AI technologies are radically transforming the global healthcare system, enabling to radically redesign the system of medical diagnostics, the development of new drugs, and generally improve the quality of healthcare services while decreasing the costs for medical clinics.

 How artificial intelligence can help doctors?

The potential of AI technologies in medicine cannot be overestimated. Neural networks are already improving the quality of medical services, increasing the efficiency of diagnostics due to the ability to work with large amounts of data.

For example, AI-powered medical chat bots help with many tasks. The service collects complaints from patients and, given the indicated symptoms, can advise on medications or make an appointment with a doctor. The collected information goes to a medical specialist who will be able to more effectively conduct the first consultation and provide the necessary assistance to the patient much faster.

AI programs are also used in X-ray analysis and drug development. Semantic Hub recently created an artificial intelligence service to assess the potential of medicines before they are released to market. The algorithm collects and analyzes scientific publications related to the disease, the purpose and action of the drug being developed. Then the AI ​​analyzes the information and makes a conclusion about the competitive advantages of the drug and the possibilities of its promotion on the market.

What are the advantages of AI in Healthcare?

AI healthcare technology improves productivity by automating tasks and can assist clinicians with quick, proper diagnoses and treatment. AI digital triage in radiology can decrease the compute time needed to create images. In population health, machine learning can better identify the likelihood of hospital readmission. Artificial intelligence in healthcare development can point to the development of new medicines. It can also make it possible to ingest data from various sources, such as medical records and important signs, and identify patterns that are hard for humans to spot.

Klinik’s technology can recognize the primary health problem, identify its urgency, and direct the patient to the right point of care in a timely, cost-effective way. AI digital triage also gives important background information for healthcare experts, enabling them to begin any medical treatment as soon as possible.

Although first aid training is a mandatory part of the education of future drivers, the time spent on this preparation is too short. Most drivers who have had a driving license for many years had this element on the course once and never refreshed this knowledge again. Already 6 months after the training, we forget the basics of erste hilfe kurs, not to mention the cyclically changing guidelines.

Car first aid kit

This is the first thing that comes to mind when we think of first aid in a traffic accident. Without the basic equipment, which is a first aid kit, your actions will be difficult or even impossible. Of course, you can use the knowledge gained in erste hilfe kurs moosach. But we guarantee you that a traffic accident suggests many problems that you must face as a first-aid driver. The mechanics of the traffic accident “does its job”, and the injuries that you will deal with are considerable.

What first aid kit for your car?

We can say that a traffic accident is a “big mess” and a lot of activities to be performed. Injuries to victims of such accidents are almost always multi-organ injuries – many ‘problems’ to be solved in a short time. Simultaneous hemorrhages, fractures, external and internal injuries. All this should be multiplied by the number of injured people. A car first aid kit should be properly equipped. In erste hilfe führerschein, students learn to use the first aid kit correctly.

As drivers, we are most interested in the DIN 13164 standard, which defines, among other things, the equipment of first aid kits used in the conditions of a road accident. DIN 13164 PLUS (+) denotes additional elements added to the basic composition of the first aid kit, most often in the form of a mouthpiece/face cloth for providing emergency rescue breaths during CPR, i.e. cardiopulmonary resuscitation.

Individuals may find their loved one needs more care than they can provide at home. When this time comes, they begin researching nursing homes. Take care when doing so, as the goal is to find a reputable facility that will provide the same level of care loved ones would provide for this person. Many people never research nursing homes until their loved one needs immediate care. They then choose a facility without thoroughly researching it to secure their spot. It’s best to take these steps before the home is needed to avoid issues.

Visit the Homes

People need to visit nursing homes rather than relying on information found online. Certain homes lack the staff needed to properly care for residents, while others serve meals that aren’t healthy for older adults. Infections run rampant in certain facilities and some places barely pass mandatory inspections. Once the loved one moves in, family members and friends quickly see these issues and may be forced to move the individual to a better facility. This can be avoided by conducting research on available facilities before one is needed.

Look at More Than the Decor

Don’t choose a facility based solely on appearance. Fancy decor or a high price tag aren’t indicators of quality care when it comes to these facilities. Safe care must be the priority regardless of the cost or the decor. Make this the most important factor when deciding to ensure your family member is treated properly at all times.

Financial Assistance

Medicare doesn’t pay for care in a nursing home unless certain criteria are met. A doctor must order this care, and the patient or their family must learn how many days their insurance will cover the stay. For instance, original Medicare only covers up to 100 days in a facility to this type, and other conditions must be met. To qualify for a second stay in a nursing home, there must be a 60-day break between admissions. Patients have the option of paying for the care out of their own pocket or attempt to qualify for Medicaid.

Ratings

Read reviews of each nursing home before making a choice. When reading Medicare reviews, don’t simply look at the star rating. Families have learned certain facilities were given five stars even when they received only one or two stars in the area of staffing levels. These levels play a significant role in the quality of the facility. On the other hand, a home may receive one star but receive five stars when it comes to staffing. Good nursing homes fill up quickly, so it’s best not to wait if a spot comes up in one of these homes.

Don’t rush through the process of choosing a nursing home for a loved one. They deserve the best care possible. When you can no longer provide this care, find someone who will. The Geoff Fraser Nursing Home is one that should never be overlooked. Here people find their family members are treated well. Staff members care for them as if they were part of their own family and that’s anyone can ask for in this situation.

R&D means research and development. It is defined as any project that tends to resolve any technological or scientific uncertainty at achieving an advance in science or technology. The one who is working under r&d pharma is termed to be scientists. They create new technology, products or services that they use or sell. They require more responsibilities and knowledge to achieve an advance in science and technology. Every year billions of money are spent under R&D. Those who are working under R&D should have more experience and knowledge about their field.

Qualification required for one to join R&D pharma industry

Pharma is a diverse field. A post-graduation in the specific area is necessary. Formulation R&D exclusively requires M.pharm candidates.

Understanding pharmaceutical research

The medical researchers are constantly trying to find some new medicines for better ways to treat the illness. They try to discover something new that may be helpful for the public and it cannot be directly put in use until it has been properly tested.

Phases under pharmaceutical research

To ensure whether the product is safe and effective in treating the diseases the pharmaceutical companies undergo a series of phases. There are three phases involved in this process. Occasionally phase 0 is carried out before phase 1and phase 4 is done after the drug is approved and is launched in the market.

Phase 0

Phase 0 is known as human micro-dose studies. It involves only a small group of participants who will be given a low, sub-therapeutic dose of the drug. Some pharmaceutical industries skip this phase and move on to phase1.

Phase 1

This stage involves a larger number of participants when compared to that of phase 0. It is the first full human study that the drug will be subject to. The safety of the participants is mainly focused on. For Phase 1 the healthy volunteers and the patients with the indicated disease are mostly preferred and the capacity of the drug is tested in them.

Phase 2

If the drug is tolerated in phase1 then it progresses to the next phase. In this phase, the number of patients has increased once again. The drug is given to the participants. During this phase, the researchers can pinpoint the side effects of the drug. Similarly, the safety of the participants is important and continues the assessments from the previous studies.

Phase 3

Phase 3 differs from phase 1 and phase 2. They concentrate more on discovering the efficacy of the drug. The phase 3 trials can be divided into two sub-stages- phase 3A and Phase 3B. When phase 3A is completed the drug manufacturers often apply for approval meanwhile they undertake phase 3B studies to obtain further safety data and further data about the drug.

Phase 4

Phase 4 is also known as a post-marketing surveillance trial. After the approval from national regulatory authorities, the drugs continue in the trial process and enter phase 4. This phase provides an opportunity for researchers to know more about the risks and benefits.

Thus r&d pharma produces more drugs for the sake of curing and preventing diseases most safely and possibly. They also see the safety, compliance, and efficiency while manufacturing medicines.

 

Women spend a substantial amount of money on healthcare compared to men. It is estimated that a 65-year-old woman will pay 20% more for healthcare throughout retirement compared to a 65-year-old man, according to a HealthView Service study. The main reason senior women pay more for healthcare is that they tend to live longer than men. It is expected for a woman to live 2.3 years longer than a man, according to Social Security’s website.

Since women live longer than men, women should plan differently for Medicare. Medicare is America’s healthcare system for seniors aged 65 or older or for people with specific disabilities. Women’s bodies consistently evolve, and preventative checkups are essential as the percentage of breast cancer and osteoporosis increase as you age. Here is why women should plan differently for Medicare.

Medicare and breast cancer

Breast cancer is the second most common form of cancer in women, according to the Centers for Disease and Prevention (CDC). Medicare is a big advocate for screenings and preventative services.  A preventive service that helps detect breast cancer is a mammogram exam, a low energy x-ray of the breast.

Medicare Part B (outpatient coverage) covers a mammogram exam at 100% once per year. If the doctor were to find something during your exam, it would be considered a diagnostic test. After you have met the deductible, you would pay a 20% coinsurance for a diagnostic mammogram exam. However, if you have a Medigap plan, your plan will likely pick up the coinsurance cost.

If you have a mastectomy, Medicare Part A (inpatient coverage) covers surgically implanted breast prostheses if the procedure takes place in an inpatient facility. However, Part B will cover the surgery if it takes place in an outpatient setting. With that said, Part B covers some external breast prostheses and a post-surgical bra after a mastectomy.

Menopause and Medicare

Women typically begin to experience menopause around age 50. Menopause is a natural decline in the production of reproductive hormones. What this means is your body is producing a drastically smaller number of hormones. Symptoms of menopause consist of hot flashes, night sweats, insomnia, and vaginal dryness.

Medicare covers hormone replacement therapy for menopause, which is used to treat menopausal symptoms. The treatment replaces the hormones that stop producing during menopause, which will ease the symptoms as well.

Hormone replacement drugs come in the form of a pill, cream, and patch, as well as a vaginal ring. Your doctor may recommend one over the other. With that said, Medicare Part B may cover the vaginal ring for hormone replacement therapy if the doctor deems the treatment medically necessary. If you receive the treatment in the form of a pill or cream, Medicare will not cover it, considering Medicare does not cover prescriptions.

Hormone replacement therapy via pill or cream will be covered by Medicare Part D (prescription drug coverage). However, each Part D plan has a different list of prescriptions they cover. If your doctor prescribes you a particular hormone replacement therapy drug, you will want to ensure that your Part D plan has that needed drug listed on the plan’s formulary.

Now, hormone replacement therapy can also reduce the possibility of developing osteoporosis.

Women with osteoporosis

Osteoporosis is a condition that makes your bones weak and fragile. Many senior women have no signs of osteoporosis until they have a bone fracture. Bone density tests can detect a decrease in your bone density and determine if you are at risk of fractures. Medicare Part B covers a bone density test once every 24 months if you meet a set of qualifying conditions.

There are injectable drugs for osteoporosis that Medicare Part A and Part B will cover. You can also have a home health nurse come to your home and inject you with the medication if you meet these conditions:

  • You have Part B and meet the home health services criteria
  • You have a bone fracture that is related to postmenopausal osteoporosis
  • You’re a woman
  • Your doctor declares that you and a family member are unable to give you the injectable drug.

You will not have any out-of-pocket costs for a home health nurse to visit your home. However, you must meet the Part B deductible and pay coinsurance for the injection’s Medicare-approved amount.

Summary

Women must look at Medicare differently as their bodies consistently evolve throughout their lives, and health conditions can arise. As you age, know that Medicare covers any service that is deemed medically necessary from a physician. For more information on Medicare coverage, contact a trusted Medicare broker, or visit medicare.gov.

With so many different diets available today, it can be difficult to know which one to use when weight loss is the goal. While the most popular diets focus on removing excess calories from the dieter’s diet by reducing intake, this isn’t always enough to shed unwanted pounds. Fortunately, there are alternatives for those looking to lose weight without resorting to fad diets that might not work.

Not everyone should use a diet to lose weight. Some illnesses could put someone at risk of developing serious health complications if they are using diet to lose weight. That is why dieting should only be done when the diet plan is medically safe for the person. That is not to say that you should avoid using the best diet plans because you might end up having problems.

Diet programs work by eliminating excessive carbohydrates and increased protein. They also limit the number of calories consumed and the amount of water consumed. By limiting food groups, the diet plans force your body to burn stored fat instead of just eating to replace the calories. In turn, your body burns more calories to produce more energy.

There are several different types of diet plans and each diet has its own set of benefits. Your doctor can help you decide which type of diet would be best for you. Below is an overview of the diet plans.

Bests Diet Plans

A low calorie diet. This diet requires the dieter to consume fewer calories per day than the maximum allowed on their diet plan. The goal is to gradually reduce calories to achieve your goal weight, and the dieter must continue to stay within the maximum daily calorie allowance for dieting.

A moderate calorie diet. In a moderate calorie diet, the dieter may be allowed to eat higher amounts of calories than they normally would, provided that they do not exceed the recommended caloric intake limit. Ina moderate calorie diet, the dieter would have to restrict their calorie intake but may not have to totally cut it out.

A strict diet. In a strict diet, the dieter is allowed to consume unlimited amounts of calories without regard to how much he or she actually needs. The dieter must adhere to the diet and does not allow any outside food.

A low carbohydrate diet. In a low carbohydrate diet, the dieter is allowed to eat high amounts of carbohydrates, but the dieter must still consume the required amount of calories. This is a weight loss diet that helps the dieter lose weight in a safe way.

A low protein diet. In a low protein diet, the dieter is allowed to eat high amounts of protein, but the dieter must still consume the required amount of calories. In a low protein diet, the dieter must follow a strict regimen and cannot consume any foods that are high in protein.

Food to Avoid To Lose Weight

Losing weight requires that the dieter avoid the foods that could be harmful to their health. As a result, the best weight loss diet plans must ensure that the dieter takes in only the right amount of calories while avoiding the foods that might be harmful to their health.

To get started on a healthy diet plan, there are several things to consider. One, you should make sure that you will be following a strict diet, but two, you should know what foods to stay away from, which is where the best weight loss diet plans can come in handy. A good diet to consider would be a custom keto diet.

Conclusion

One of the most important things you can do is make sure that you are staying on track with your diet. You should choose a diet plan based on your personal preferences, as well as knowing the foods that you should stay away from.