R&D means research and development. It is defined as any project that tends to resolve any technological or scientific uncertainty at achieving an advance in science or technology. The one who is working under r&d pharma is termed to be scientists. They create new technology, products or services that they use or sell. They require more responsibilities and knowledge to achieve an advance in science and technology. Every year billions of money are spent under R&D. Those who are working under R&D should have more experience and knowledge about their field.
Qualification required for one to join R&D pharma industry
Pharma is a diverse field. A post-graduation in the specific area is necessary. Formulation R&D exclusively requires M.pharm candidates.
Understanding pharmaceutical research
The medical researchers are constantly trying to find some new medicines for better ways to treat the illness. They try to discover something new that may be helpful for the public and it cannot be directly put in use until it has been properly tested.
Phases under pharmaceutical research
To ensure whether the product is safe and effective in treating the diseases the pharmaceutical companies undergo a series of phases. There are three phases involved in this process. Occasionally phase 0 is carried out before phase 1and phase 4 is done after the drug is approved and is launched in the market.
Phase 0 is known as human micro-dose studies. It involves only a small group of participants who will be given a low, sub-therapeutic dose of the drug. Some pharmaceutical industries skip this phase and move on to phase1.
This stage involves a larger number of participants when compared to that of phase 0. It is the first full human study that the drug will be subject to. The safety of the participants is mainly focused on. For Phase 1 the healthy volunteers and the patients with the indicated disease are mostly preferred and the capacity of the drug is tested in them.
If the drug is tolerated in phase1 then it progresses to the next phase. In this phase, the number of patients has increased once again. The drug is given to the participants. During this phase, the researchers can pinpoint the side effects of the drug. Similarly, the safety of the participants is important and continues the assessments from the previous studies.
Phase 3 differs from phase 1 and phase 2. They concentrate more on discovering the efficacy of the drug. The phase 3 trials can be divided into two sub-stages- phase 3A and Phase 3B. When phase 3A is completed the drug manufacturers often apply for approval meanwhile they undertake phase 3B studies to obtain further safety data and further data about the drug.
Phase 4 is also known as a post-marketing surveillance trial. After the approval from national regulatory authorities, the drugs continue in the trial process and enter phase 4. This phase provides an opportunity for researchers to know more about the risks and benefits.
Thus r&d pharma produces more drugs for the sake of curing and preventing diseases most safely and possibly. They also see the safety, compliance, and efficiency while manufacturing medicines.